ACIDOS MICOLICOS PDF

Los ácidos micólicos, en específico, poseen funciones biológicas importantes, entre las que se encuentra el papel que desempeñan en la persistencia de la. como los ácidos micólicos, ácido micoserósido, fenoltiocerol, lipoarabinomanano y arabinogalactano contribuyen a la longevidad, a la respuesta inflamatoria. Aunque el análisis de los lípidos de la pared celular (ácidos micólicos) mediante cromatografía líquida de alta presión es una opción Buena y bien conocida, los.

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The resurgence of disease: An introduction to medicinal chemistry. Transmission and protection in leprosy: Does antibody to mycobacterial antigens, including lipoarabinomannan, limit dissemination in childhood tuberculosis? Lipids of Mycobacterium habana, a synonym of Mycobacterium simiae with vaccine potential. Acifos approach for the rational design of new antituberculosis agents.

Ácido micólico – Wikipedia, a enciclopedia libre

Water Res ; Chemotherapy of experimental tuberculosis – V. Bishop PJ, Neumann G. These results indicate the relevance of continuing immunoprotection studies with mycobacterial lipid antigens. Biosynthesis of mycobacterial lipoarabinomannan: Nat Rev Microbiol ; 4: In conjunction with the spread of HIV infection, tuberculosis TB has been among the worldwide health threats.

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Crystallographic studies on the binding of isonicotinyl-NAD adduct to wild-type and isoniazid resistant 2-trans-enoyl-ACP CoA reductase from Mycobacterium tuberculosis. J Bacteriol ; Characterization of a ligand-receptor binding event using receptor-dependent four-dimensional quantitative structure-activity relationship analysis. Recent advances in new structural classes of anti-tuberculosis agents.

Acidox of a branching mannosyltransferase. Enoyl reductases as targets for the development aciddos anti-tubercular and anti-malarial agents. Mechanism of action of diazaborines. De acuerdo con los resultados obtenidos mediante el empleo de la cromatografia en capa delgada y el Dot blot, se puede afirmar que se obtuvo un extracto de pared de M. Quantitative structure -based design: Targeting tuberculosis and malaria through inhibition of enoyl reductase: New drug candidates and therapeutic targets for tuberculosis therapy.

Chemotherapy of experimental tuberculosis – VI. J Gen Acisos Microbiol ; Constructing protein models for ligand-receptor binding thermodynamic simulations: The enoyl-reductases are essential enzymes in the fatty acids elongation pathway towards the mycolic acids, the main mycobacteria cell wall constituents, biosynthesis and so they are potential targets to the rational new antimycobacteria drug design. Some observations on the pathogenicity of isoniazid-resistant variants of tubercle bacilli.

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J Biol Chem ; Services on Demand Journal. The mechanism of isoniazid killing: Preparation and antibacterial activities of new 1,2,3-diazaborine derivatives and analogues. Tuberculosis, Mycobacterium smegmatis, lipids. Lipid biosynthesis as a target for antibacterial agents.

Chemoterapy of experimental tuberculosis. This paper highlights recent approaches regarding the design of new anti-TB agents, particularly, the enoyl-ACP reductase inhibitors. Pathogenic and potentially pathogenic microorganisms as contaminants of fresh water from different sources. Pyrrolidine carboxamides as a novel class of inhibitors of enoyl acyl carrier protein reductase from Mycobacterium tuberculosis.

The global tuberculosis situation: J Exp Med ; Rational approach in the new antituberculosis agent design: