Amphipterygium adstringens is a plant widely used in Mexican traditional medicine for its known anti-inflammatory and antiulcer properties. Amphipterygium adstringens is a deciduous shrub or small tree, commonly growing about 3 – 6 metres tall, with a broad and rather flat or sometimes narrow . PDF | Extracts from the bark of Amphipterygium adstringens, known as Cuachalalate, is in Mexico commonly used to treat several gastrointestinal disorders.

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Porphyromonas gingivalis and Aggregatibacter actinomycetemcomitans are bacteria often isolated from the subgingival biofilm [ 3031 ] and associated with periodontitis and gingivitis. Preparations and formulations of this CE can be improved and applied for daily use in dental products to prevent caries and periodontal diseases and concomitantly weaken the risk of cancer. Images were obtained at 10 and 40x magnification b and c.

With this approach, we studied the antimicrobial activity of CE of A. This article has been cited by other articles in PMC.

Open in a separate window. Articles from Mediators of Inflammation are provided here courtesy of Hindawi Limited. There exists an increasing prevalence of infections worldwide, due to, among other reasons, the growing resistance of pathogens to antibiotics and antifungals as well as alterations in the autoimmune system.

The distinguishing factor of this tree adstringems its bark. Total Flavonoid Content The Dowd method [ 23 ] was used to determine the flavonoid content. View at Google Scholar M. The minimum inhibitory concentrations MIC were determined by microdilution broth method according to the Clinical and Laboratory Standards Institute [ 49 ], using well plates. Food and Chemical Toxicology. Therefore, our findings indicate that AaEE treatment of colitis might be reducing the extent of colonic injury by its antioxidant ability.

It is an effective antiplaque agent developed to date, but it has been proven that prolonged use causes several undesirable side effects; besides many clinical trials have shown that taste of chlorhexidine is not well accepted by children [ 52 ].


The mortality in the DSS group started at day 13, Although all of them have shown some grade of efficacy in these intestinal conditions, the frequency and severity of adverse effects, inconvenient dosing regimen, and partially prohibitive price limit their long-term use [ 34 ].

Amphipterygium adstringens Scientific classification Kingdom: Journal List Mediators Inflamm v. Gastroprotective activity of Nigella sativa L oil and its constituent, thymoquinone against acute alcohol-induced gastric mucosal injury in rats. Cytokine blockade in inflammatory bowel diseases. The peak areas were measured by electronic integration.

In regard of activity shown against S. Table of Contents Alerts. This observation suggests that A. At the end of the experimental period, the clinical symptoms were more pronounced.

Use of medicinal plants in Monterrey, Mexico. Adalimumab in Crohn’s disease: Discussion The standard treatments for colitis are generally immunosuppressant and anti- inflammatory drugs, which have many undesirable side effects.

In Vitro Antimicrobial and Antiproliferative Activity of Amphipterygium adstringens

Published online Aug Ameliorative effects of 3,4-oxo-isopropylidene-shikimic acid on experimental colitis and their mechanisms in rats. The lowest concentration of the subculture with no growth was considered the minimum bactericidal concentration MBC or the minimum fungicidal concentration MFC.

The cell line has less than 20 passages as laboratory good practices. The male inflorescence is about 8. Retrieved from ” https: A wide range of uses and diversity of biological activities reported reminds us of a complex mixture of multitarget compounds, which is a common characteristic in several medicinal plants and similar to others [ 22 ].

Antioxidant, antimicrobial and cytotoxic activities of selected medicinal plants from Yemen. Plant Material The A. Additionally, the constantly observed correlation between oral microbiome especially biofilm builders [ 28 ] with chronic inflammatory disease and cancer triggers the need for further research adstriingens contributes with novel sources of bioactive compounds.


In this grading system, inflammation severity was scored on a 0—3 scale 0: Therefore, the present study aimed to investigate the antioxidant, anti-inflammatory, and immunomodulatory activities of A.

The stamen is short, with a filament averaging at only. Trees and Shrubs of Mexico pt. Body weight loss and bloody stools were observed in mice acutely exposed to DSS.

Histopathological scores were analyzed from slides a. As mentioned before, oral microbiota diversity is closely related to health conditions and systemic diseases such as cardiovascular and inflammatory diseases and cancer. The scoring system yields minimal and ajphipterygium total scores of 0 and 9. Then 5 micrometer-thick tissue sections were prepared and stained with hematoxylin and eosin HE to evaluate mucosal damage.

The reduction of pathogens associated with systemic and oral infections, using natural products to inhibit the ability to form biofilms, could be an effective approach to prevent and control oral diseases. Probability values of axstringens considered to be significant. The main clinical manifestations produced by the model of acute DSS colitis are diarrhea and blood in the stool, always accompanied by considerable weight loss.

Principles of the bark of Amphipterygium adstringens (Julianaceae) with anti-inflammatory activity.

We determine the effect of AaEE on clinical features disease activity indexantioxidants, anti-inflammatory, and immunomodulatory activities in relation to the activity of SOD, CAT, and GPx, levels of proinflammatory cytokines, and changes both macroscopic and microscopic of the colonic mucosa.

The Female inflorescence is in raceme about 1. Melatonin adshringens ethanol-induced gastric mucosal damage possibly due to its antioxidant effect.