The leaf of Costus pictus D. Don is considered as an antidiabetic in folklore medicine and is known to reduce the blood sugar, similar to insulin. PDF | To explore the micro morphology and physicochemical parameters of the leaves of Costus pictus D. Don (Costaceae). Macroscopy. Painted Spiral Ginger is a perennial herb, native to Mexico. It has long narrow leaves with a characteristic wavy edges. The bases of the sheaths are mottled with.

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Liquid chromatography—mass spectrometry analysis of Costus pictus extract The experiment was carried out using an Agilent Infinity ultrahigh-performance liquid chromatography HPLC. Our endeavor as a genomics company is not to make a new drug, but to make sure that there is enough proof-of-concept to take it to a level that will interest the pharma industry.

Use of a free radical method to evaluate antioxidant activity. The presence of oxidative stress coshus augments the hepatic and renal damage caused due to thyroid hormone insufficiency.

Costus pictus ‘Red Stem’

Hypoglycemic potential of Morus Indico L. Thyroidectomized cistus model was not used because in thyroidectomized rats there is danger of removal of associated parathyroid glands resulting in tetany. This is the first study to reveal that C.

In the general population, the major cause for hypothyroidism is autoimmune thyroiditis. PTU is a reversible goitrogen. Management of type 2 diabetes: Shankar P, Sundarka MK.


Plasma ALT level showed an increase, but it was not significant.

Animal experiments The study was conducted in the Department of Biochemistry, JIPMER, Puducherry, India, after obtaining approval from the institutional animal ethics and scientific advisory committees. Tell a friend about this flower! Fruits in L-6 cell lines. Insulin plant in gardens. Treatment with Costus pictus leaf extract in hypothyroid rats significantly improved the thyroid profile. Hypothyroid group showed a profound elevation in both total cholesterol 1.

Drug Des Costuss Ther. Treatment with Costus pictus leaf extract in hypothyroid rats significantly improved the thyroid profile. We found that administration of C.

Costus pictus – Wikidata

Indian J Physiol Pharmacol ; To conclusively prove the aforementioned mechanism, further investigations on expression and activity of thyroperoxidase and 5’deiodinase in the thyroid gland and metabolism of PTU on treatment with C. Dr Rao commented that, “Since large portions of the transcripts are involved in bixin biosynthesis in costuw plant, we believe this is implicated in anti-diabetic properties of the leaves”. Costaceae Spiral Ginger family Synonyms: We have reported in our earlier studies with C.

The absorbance of each reaction mixture was measured at nm. Alpha and beta amyrins possess potent anti-inflammatory, antioxidant, hepatoprotective, and anti-nociceptive effects. He has more than 20 years of teaching and research experience.

Blood samples were collected at the beginning and end of the study. The increase in absorbance at nm was measured. The challenge is that the functional annotation of identified transcripts or RNA is key to elucidating the mode-of-action and this is a bigger challenge for plants. The difference in mean values among the groups was analyzed using one-way analysis of variance ANOVA with Bonferroni post hoc test for anthropometric parameters, tissue oxidative stress markers and plasma inflammatory markers.


Therapeutic exploration of betulinic acid in chemically induced hypothyroidism. The mechanism of action of the thioureylene antithyroid drugs. Plethora of human and animal studies have proved that hypothyroidism is associated with elevated plasma total cholesterol levels. The IC 50 value of positive control ascorbic acid was found to be 6.

Rats were then injected 2. Cell lines in diabetes. MDA was measured according to the method described by Ohkawa et al. Ethanolic extract of C.

Hypothyroidism leads to perturbed liver and kidney function. The IC 50 value of C. The data identified transcripts related to pathways of bixin, geranial and geraniol biosynthesis which are known to be peroxixome proliferator activated receptors PPAR agonists and anti-glycation agents.

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Assessment of hepatic and renal oxidative stress Liver and kidney tissues were homogenized using 0. Lower absorbance of the reaction mixture indicates higher free radical scavenging activity.

Don is considered as an antidiabetic in folklore medicine and is known to reduce the blood sugar, similar to insulin.

Culture of animal cells: