Concepto de RCIU, Clasificación: PEG, RCIU. Etiología, Fisiopatología, Diagnóstico, Manejo, Pronóstico. Concept of IUGR, Classification: SGA. Dra. Sofía Córdoba V. Residente II Año Ginecología y Obstetricia HCG Tutor: Dr. Manrique Leal M. Fisiopatología del RCIU mediante el. 14 ago. Objetivos específicos: • Compreender a fisiopatologia da doença, sua RCIU: Gemelares monocoriônicos > Dicoriônicos > gestações únicas.
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Figure 1 – Mean weight of newborn rats from the control group, the group submitted to dietary restriction from the 1st day and the group submitted to dietary restriction after the 3rd day of pregnancy, as determined on the 18th and 21st days of pregnancy.
Maternal protein-calorie malnutrition was the cause of IUGR in rats, with the following physiopathologic peculiarities:. La media de la edad gestacional para los grupos de RCIU y control fueron 35,7 y 36,2 semanas, respectivamente. Cierre el abdomen en dos capas utilizando un funcionamiento continuo sutura de poliglactina Vicryl Ethicon, Johnson y Johnson Medical, EE.
Experimental research carried out in Botucatu Brazil has demonstrated that fetuses with IUGR are obtained using models of protein-calorie malnutrition, of maternal arterial hypertension and of severe maternal diabetes. This leads to the removal of glycogen deposited in the placenta which, converted into energy, increases the weight of newborn rats.
A more in-depth study of the placenta and pancreas of newborn rats has permitted the understanding of the deviations in fetal growth occurring in the presence of moderate and severe diabetes.
Intrauterine growth retard IUGR continues to be a significant fisioaptologia problem at the end of this century. To assess indexes and velocities rcou the uterine artery as indicators of uterine hypoperfusion in pregnant women with intrauterine growth restriction. This is probably due to the vicarious action of the placenta occurring with its increased weight Figures 1 and 2. When the restricted groups were compared with each other, the percentage of SGA young was higher in the group submitted to dietary restriction from the 1st day of pregnancy.
We recommend downloading the newest version of Flash here, but we support all versions 10 and above. Early pregnancy changes in hemodynamics and volume homeostasis are consecutive eciu triggered by a primary fall in systemic vascular tone. Figure 3 – Percentage of small for gestational age newborn rats from the control fisiopatologiq, the group submitted to dietary restriction from the 1st day and the group submitted to dietary restriction after the 3rd day of pregnancy, as determined on the 18th and 21st days of pregnancy.
Si la bradicardia fetal es persistente, el examen de esta feTus debe ser abandonada a favor de examinar visiopatologia siguiente feto. The thickness of the placental exchange surface decreased from the 18th to the 21st day of pregnancy in all groups studied, but the placentas did not differ in terms of quantity of cytotrophoblastic cells.
After pregnancy was confirmed, 11 the rats were assigned at random to the following experimental groups according to the diet used and the rdiu age at the time of resolutioni. Br J Fisiopatoloia ; Placental glycogen stores also decreased after the 18th day in the control groups and in the groups submitted to dietary restriction from the 1st day of pregnancy.
Rheological and physiological consequences of conversion of the maternal spiral arteries for uteroplacental blood flow during human pregnancy.
RCIU: by sofia cordoba on Prezi
Please check your Internet connection and reload this page. Unable to load video. The placentas of rats submitted to dietary restriction were larger than those rcuu the control on the 18th day of pregnancy. Doppler investigation of uteroplacental blood flow resistance in the second trimester: Br J Obstet Gynecol.
Fisiopatologia rciu pdf file
Maternal growth factor regulation of human placental development and fetal growth. The material was embedded in paraffin, sectioned and stained with hematoxylin-eosin HE. The continuation of maternal malnutrition up to the 21st day was associated with decreased fetal weight and increased incidence of intrauterine growth retardation even rrciu placental weight was maintained and glycogen stores evolved normally.
Los resultados representativos de los estudios Doppler fetoplacentaria se muestran en la Figura 2. Calderon 12 demonstrated that the endocrine pancreas of newborn rats with moderate diabetes has large islets with increased insulin production, as observed by fiisiopatologia using specific antibodies. Evidence for altered placental blood flow and vascularity in compromised pregnancies.
Newborn rats with severe diabetes showed increased glycogen deposition in the placenta from the 18th to the 21st day of pregnancy. Ten Langerhans islets per slide were analyzed in terms of size, borders and quantity of fisiopatologiia in the cell cytoplasm. Los autores desean agradecer al Dr. Duvekot J, Peeters I. J Dev Orig Health Dis.
Uterine artery indexes and velocities indicators of uterine hypoperfusion in pregnant women with intrauterine growth restriction.
On the 18th day of pregnancy, mean newborn weight was higher in the group submitted to dietary restriction after the 3rd day. Doppler velocimetry of the uterine artery as a screening rdiu for gestational hypertension.
In the groups submitted to dietary restriction from the 1st day of pregnancy, fetal development was normal up to the 18th day because of the vicarious action of the placenta and of the glycogen stores.
The material was stained with HE and morphology was compared between the experimental groups. Int J Mol Sci. In the pancreas of newborn rats with severe diabetes the islets are large but have no insulin-positive cells and therefore their insulin production is depleted. Am J Obstet Gynecol.
Your institution must subscribe to JoVE’s Flsiopatologia section to access this content. A subscription to J o VE is required to view this article. Fisiiopatologia 6 – Placentas of rats receiving the diet ad libitum A and of rats submitted to protein-calorie restriction from the 1st day B and after the 3rd day of pregnancy Cobtained on the 18th day of pregnancy – in Hematoxylin-Eosin and Periodic Acid Schiff.
Ultrasonography in Experimental Reproductive Investigations on Rats. For other languages click here. Placental transport in response to altered maternal nutrition. Fill out the form below to receive a free trial or learn more about access: You must be signed in to post a comment.
Protein-calorie restriction after the 3rd day of pregnancy reduced glycogen stores in the placenta and fetal development. Diabetes and experimental pregnancy in rats: Thirty pregnant women with intrauterine growth restriction IUGR confirmed birthweight below the 10th percentile; the control group included 80 normal pregnant women in the third trimester. J Ped ;46 1: